diff --git a/dev-python/pillow-heif/Manifest b/dev-python/pillow-heif/Manifest
index eb79d4e0a9..8d4ad21d22 100644
--- a/dev-python/pillow-heif/Manifest
+++ b/dev-python/pillow-heif/Manifest
@@ -1 +1,2 @@
 DIST pillow_heif-0.21.0.tar.gz 16178019 BLAKE2B 1ac057f4485331c36348f277b31d073dfe5d3aab69baaef0947449002fb095c81ffd562442f059afc29a19cafb3fa898b011c17a622963e6813a53dd2779c2f7 SHA512 9683b3eea9ea4dc0730bfab2e1163545ea31719b62cfd90a4f58aaf7ab401aef27afb7b9458c93daf9e5fa445b8f7f1ec3b3174fa9ae44513d9baaa10e777913
+DIST pillow_heif-0.22.0.tar.gz 18551571 BLAKE2B 60edcd7f1e6427651f85a2d8604b2a478646ba90cc1aeb09b768b7cf94b333d14e0d0d118d26d7ef68e6a79873d2d18f7f85ad0ae02ae81b8298e6c758ae01d0 SHA512 072de5e3afbfb373e36b51898f67e12d1abcd9a391e33b2dafe19372bb0f3ffca20ab1a7f7f8dcd0dc163a7c8aee27040613deb5d2adba0fd3b6c774cbff8c85
diff --git a/dev-python/pillow-heif/pillow-heif-0.22.0.ebuild b/dev-python/pillow-heif/pillow-heif-0.22.0.ebuild
new file mode 100644
index 0000000000..cebb12170b
--- /dev/null
+++ b/dev-python/pillow-heif/pillow-heif-0.22.0.ebuild
@@ -0,0 +1,47 @@
+# Copyright 2024-2025 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_EXT=1
+DISTUTILS_USE_PEP517=setuptools
+PYTHON_COMPAT=( python3_{11..13} )
+inherit distutils-r1 pypi
+
+DESCRIPTION="Python interface for libheif library"
+HOMEPAGE="
+	https://github.com/bigcat88/pillow_heif
+	https://pypi.org/project/pillow-heif/
+"
+
+LICENSE="BSD"
+SLOT="0"
+KEYWORDS="~amd64"
+
+RDEPEND="
+	!test? (
+		dev-python/pillow[${PYTHON_USEDEP}]
+		>=media-libs/libheif-1.17.6:=
+	)
+	test? (
+		dev-python/pillow[jpeg,lcms,webp,zlib,${PYTHON_USEDEP}]
+		>=media-libs/libheif-1.17.6:=[x265]
+	)
+"
+BDEPEND="
+	test? (
+		dev-python/defusedxml[${PYTHON_USEDEP}]
+		dev-python/numpy[${PYTHON_USEDEP}]
+		media-libs/opencv[png,python,${PYTHON_USEDEP}]
+	)
+"
+
+PATCHES=( "${FILESDIR}/${PN}-0.21.0-respect-cflags.patch" )
+
+EPYTEST_DESELECT=(
+	# only works with libeif-1.19.5
+	# https://github.com/bigcat88/pillow_heif/pull/312/commits/d740dcce7d967d025c4100611cc7a4632aa3fc3a
+	"tests/read_test.py::test_heif_read_images"
+)
+
+distutils_enable_tests pytest