diff --git a/dev-python/pyodbc/Manifest b/dev-python/pyodbc/Manifest
deleted file mode 100644
index 2159c38d9e..0000000000
--- a/dev-python/pyodbc/Manifest
+++ /dev/null
@@ -1 +0,0 @@
-DIST pyodbc-5.1.0.tar.gz 115450 BLAKE2B 8080db700abb952ae60045825f76e73a3d4a42f13c05e48eeb06574d5535f34345aa8bf2710730430229cb31b3d73c9fcb250d8d0fddabf94ecfcb24518bf931 SHA512 78817864d30048eed0c670a30e1cc66bc72edd6c21d069a5cc5831ed180b25a5b30d2bf2313628431943defbae66c2df96e90781ef17bb8929622b9f49cfcaab
diff --git a/dev-python/pyodbc/metadata.xml b/dev-python/pyodbc/metadata.xml
deleted file mode 100644
index ee51824dad..0000000000
--- a/dev-python/pyodbc/metadata.xml
+++ /dev/null
@@ -1,10 +0,0 @@
-<?xml version="1.0" encoding="UTF-8"?>
-<!DOCTYPE pkgmetadata SYSTEM "https://www.gentoo.org/dtd/metadata.dtd">
-<pkgmetadata>
-  <!-- maintainer-needed -->
-  <upstream>
-    <bugs-to>https://github.com/mkleehammer/pyodbc/issues</bugs-to>
-    <remote-id type="pypi">pyodbc</remote-id>
-    <remote-id type="github">mkleehammer/pyodbc</remote-id>
-  </upstream>
-</pkgmetadata>
diff --git a/dev-python/pyodbc/pyodbc-5.1.0.ebuild b/dev-python/pyodbc/pyodbc-5.1.0.ebuild
deleted file mode 100644
index 59ab333e28..0000000000
--- a/dev-python/pyodbc/pyodbc-5.1.0.ebuild
+++ /dev/null
@@ -1,64 +0,0 @@
-# Copyright 1999-2024 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=8
-
-DISTUTILS_EXT=1
-DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{11..12} ) #py3.13 doesn't compile
-
-inherit databases distutils-r1 optfeature pypi
-
-DESCRIPTION="Python ODBC library"
-HOMEPAGE="
-	https://pypi.org/project/pyodbc/
-	https://github.com/mkleehammer/pyodbc
-"
-
-LICENSE="MIT"
-SLOT="0"
-KEYWORDS="~amd64"
-IUSE="mssql"
-
-RDEPEND=">=dev-db/unixODBC-2.3.0"
-DEPEND="${RDEPEND}"
-BDEPEND="
-	test? (
-		${DATABASES_DEPEND[mysql]}
-		dev-db/myodbc:8.0
-	)
-"
-
-distutils_enable_tests pytest
-
-EPYTEST_DESELECT=(
-	# Broken test, generates a string longer than 4000 characters
-	tests/mysql_test.py::test_varchar
-)
-
-EPYTEST_IGNORE=(
-	# No easy way to run an SqlServer during tests
-	tests/sqlserver_test.py
-)
-
-python_test() {
-	export PYODBC_MYSQL="DRIVER=/usr/$(get_libdir)/myodbc-8.0/libmyodbc8a.so;SERVER=localhost;PORT=44444;DATABASE=test"
-	export PYODBC_POSTGRESQL="DRIVER=/usr/$(get_libdir)/psqlodbcw.so;SERVER=localhost;PORT=44445;DATABASE=test;UID=postgres"
-	epytest
-}
-
-src_test() {
-	emysql --start 44444
-	epostgres --start 44445
-	psql -U postgres -h 127.0.0.1 -p 44445 <<EOF
-CREATE DATABASE test OWNER postgres
-EOF
-	distutils-r1_src_test
-	epostgres --stop
-	emysql --stop
-}
-
-pkg_postinst() {
-	optfeature "MySQL support" dev-db/myodbc
-	optfeature "PostgreSQL support" dev-db/psqlodbc
-}
diff --git a/profiles/package.mask b/profiles/package.mask
index 2638c2224f..f3de1de21b 100644
--- a/profiles/package.mask
+++ b/profiles/package.mask
@@ -118,11 +118,6 @@ dev-python/stdlibs
 # Removal on 2025-04-05.
 dev-python/sphinx-argparse-cli
 
-# Anna (cybertailor) Vyalkova <cyber+gentoo@sysrq.in> (2025-03-05)
-# Unmaintained in GURU, no revdeps left. Open bugs: #931931.
-# Removal on 2025-04-05.
-dev-python/pyodbc
-
 # Julien Roy <julien@jroy.ca> (2024-03-21)
 # sys-libs/libucontext is masked in ::gentoo
 sys-libs/gcompat