diff --git a/dev-python/opentelemetry-instrumentation/Manifest b/dev-python/opentelemetry-instrumentation/Manifest
index 5a4bc1c3be..d66e38eaad 100644
--- a/dev-python/opentelemetry-instrumentation/Manifest
+++ b/dev-python/opentelemetry-instrumentation/Manifest
@@ -1,4 +1,6 @@
 DIST opentelemetry-python-1.43.0.gh.tar.gz 1601072 BLAKE2B 9ea017308ecc0e3d4b00b86bf384c8737341babe5690defd33f0455af248052a4492bcaa793ea5a2bdc7a2d1cc27a708631651b232bda788fb535a7581bf844a SHA512 ec8b5862f9bc8aaa60ff765cbdf72ce488ea8b04efa49549901d73b909f5f66a187e8e345ac8b085fdff03207787539ff6a6f75ceb8fdbc056a5de5c3c3619ab
 DIST opentelemetry-python-1.44.0.gh.tar.gz 1651335 BLAKE2B 9b1e6b9dbabaeccfc1e9fc267de0c882c78816abdec6d5344deccecca2c6d41736e1eb2fa7b5d85ed2e0047fa8fe23db1f4d2ae8e561f9c44ea1413754dde7f9 SHA512 310fa4d7b11aa6a4cfb498294e3c71e082e8fe2a9899c855f0968eb0b6eff91fc66921a0dad3b2075944a6f21b8802aea7d58baefd916f7909f1dae30bc7ad61
+DIST opentelemetry-python-1.45.0.gh.tar.gz 1715368 BLAKE2B 6a70a94f38df7b038eca1cf815ca93deaf58c94aac0996a24d08a0f9243651dd1e0c8c4f7daf9b1bc6274677ed1519fa0e9e72243fe266765a43fc6d50a4301a SHA512 c05f1fd1f6b2f8de830d2d2bdbaac01c47aa0b4615091f6fd78c39ef7e4aba10c2bd23ef4906e5b9e4ab46b2e55f8321f917c900bb930988d1cdfc85e9a77527
 DIST opentelemetry-python-contrib-0.64b0.gh.tar.gz 1983357 BLAKE2B 5889183d317ac2afcbb44f6df7ffabf20094b9fb56aa8f2c578b6fa66b76ded2cf63b0488594719cc231997e9d6b6d042fd7d83df8f192b9904367e65c623333 SHA512 78bc185a0d41c0dfd261d6cc4204e98c09b1bc8598cbab77890f559c5a84fdfacc95952c1358790f2b588540b60016f7ffea6d80b398e07d73af888e4c4bbfa9
 DIST opentelemetry-python-contrib-0.65b0.gh.tar.gz 2031667 BLAKE2B 2e932229b81d9958fd6941c90315977c9d28b4652a8ec1b1b32bda064b70d059611a0a2142ec63739eebaed92ee7744f8fbba38a251aed7f16451f8180831fa4 SHA512 0086da20862b5be310594313e59927e508fbbfe36a3dee1ef8759f44b37ac8b2e7dbd31c1d27bd44a86a413c7aa8ec6a0c24ca31584433913fdd4b83fd089693
+DIST opentelemetry-python-contrib-0.66b0.gh.tar.gz 1875879 BLAKE2B e92e5d89674197cbed378c3c48eb78bbfc87cd6f0ab97881b0f990c5fa5294d94aea49953e9db384a3c6b4853c0cb3a3f8d3f16a49dc6e3eec426837ed4cdc28 SHA512 58da31c4cda5c0464f3dcd3ec99b97575a7742ec7e419a88279cb1ba830041659118e9d62a8e6d22205bbd2c7b8130859babe5faa626ec107b61c9130b79c087
diff --git a/dev-python/opentelemetry-instrumentation/opentelemetry-instrumentation-0.66_beta0.ebuild b/dev-python/opentelemetry-instrumentation/opentelemetry-instrumentation-0.66_beta0.ebuild
new file mode 100644
index 0000000000..9459fc40f2
--- /dev/null
+++ b/dev-python/opentelemetry-instrumentation/opentelemetry-instrumentation-0.66_beta0.ebuild
@@ -0,0 +1,59 @@
+# Copyright 2026 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_USE_PEP517=hatchling
+PYTHON_COMPAT=( python3_{12..15} )
+
+inherit distutils-r1
+
+MY_PV=${PV/_beta/b}
+MY_P="opentelemetry-python-contrib-${MY_PV}"
+
+OTLP_PV=1.45.0
+OTLP_P="opentelemetry-python-${OTLP_PV}"
+
+DESCRIPTION="Instrumentation Tools & Auto Instrumentation for OpenTelemetry Python"
+HOMEPAGE="
+	https://opentelemetry.io/
+	https://pypi.org/project/opentelemetry-instrumentation/
+	https://github.com/open-telemetry/opentelemetry-python-contrib/
+"
+SRC_URI="
+	https://github.com/open-telemetry/opentelemetry-python-contrib/archive/refs/tags/v${MY_PV}.tar.gz
+		-> ${MY_P}.gh.tar.gz
+	test? (
+		https://github.com/open-telemetry/opentelemetry-python/archive/refs/tags/v${OTLP_PV}.tar.gz
+			-> ${OTLP_P}.gh.tar.gz
+	)
+"
+S="${WORKDIR}/${MY_P}/${PN}"
+
+LICENSE="Apache-2.0"
+SLOT="0"
+KEYWORDS="~amd64 ~arm64 ~x86"
+
+RDEPEND="
+	~dev-python/opentelemetry-api-${OTLP_PV}[${PYTHON_USEDEP}]
+	~dev-python/opentelemetry-sdk-${OTLP_PV}[${PYTHON_USEDEP}]
+	~dev-python/opentelemetry-semantic-conventions-${OTLP_PV}[${PYTHON_USEDEP}]
+	>=dev-python/packaging-18.0[${PYTHON_USEDEP}]
+	>=dev-python/wrapt-1.0.0[${PYTHON_USEDEP}]
+"
+
+EPYTEST_PLUGINS=()
+distutils_enable_tests pytest
+
+python_test() {
+	cp -a "${BUILD_DIR}"/{install,test} || die
+	local -x PATH=${BUILD_DIR}/test/usr/bin:${PATH}
+
+	for dep in tests/opentelemetry-test-utils; do
+		pushd "${WORKDIR}/${OTLP_P}/${dep}" >/dev/null || die
+		distutils_pep517_install "${BUILD_DIR}"/test
+		popd >/dev/null || die
+	done
+
+	epytest
+}