diff --git a/dev-python/opentype-sanitizer/Manifest b/dev-python/opentype-sanitizer/Manifest
deleted file mode 100644
index cbf8aea967..0000000000
--- a/dev-python/opentype-sanitizer/Manifest
+++ /dev/null
@@ -1 +0,0 @@
-DIST opentype-sanitizer-9.1.0.tar.gz 159945 BLAKE2B ae223dbca34bcad0ec656691be85b01b2d3beda5965b06e7c617742aa6a93f7d9adf4e6f3df9d454c29afbd24e4493580bb19dab1e76b7a218d942287d1b8408 SHA512 d995a1d30591726065d18b5c2eda817b01effe637ab2013c927238e75810ff215088801c4bcdd7dec43cfcf5043f3669ae2ed6502ded834c8f3c8cfe712354e9
diff --git a/dev-python/opentype-sanitizer/metadata.xml b/dev-python/opentype-sanitizer/metadata.xml
deleted file mode 100644
index 7e101cb700..0000000000
--- a/dev-python/opentype-sanitizer/metadata.xml
+++ /dev/null
@@ -1,9 +0,0 @@
-<?xml version="1.0" encoding="UTF-8"?>
-<!DOCTYPE pkgmetadata SYSTEM "https://www.gentoo.org/dtd/metadata.dtd">
-<pkgmetadata>
-	<!-- maintainer-needed -->
-	<upstream>
-		<remote-id type="pypi">opentype-sanitizer</remote-id>
-		<remote-id type="github">googlefonts/ots-python</remote-id>
-	</upstream>
-</pkgmetadata>
diff --git a/dev-python/opentype-sanitizer/opentype-sanitizer-9.1.0.ebuild b/dev-python/opentype-sanitizer/opentype-sanitizer-9.1.0.ebuild
deleted file mode 100644
index d1dd4c3e35..0000000000
--- a/dev-python/opentype-sanitizer/opentype-sanitizer-9.1.0.ebuild
+++ /dev/null
@@ -1,32 +0,0 @@
-# Copyright 2023-2024 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=8
-
-PYTHON_COMPAT=( python3_{11..12} )
-DISTUTILS_USE_PEP517=setuptools
-DISTUTILS_EXT=1
-PYPI_NO_NORMALIZE=1
-inherit distutils-r1 pypi
-
-DESCRIPTION="Python wrapper for the OpenType Sanitizer"
-HOMEPAGE="
-	https://pypi.org/project/opentype-sanitizer/
-	https://github.com/googlefonts/ots-python
-"
-
-LICENSE="BSD"
-SLOT="0"
-KEYWORDS="~amd64"
-
-RDEPEND="
-	app-arch/lz4:=
-	media-libs/woff2
-	sys-libs/zlib:=
-"
-DEPEND="${RDEPEND}
-	dev-cpp/gtest
-"
-BDEPEND="dev-build/meson"
-
-distutils_enable_tests pytest
diff --git a/profiles/package.mask b/profiles/package.mask
index e5671b2268..ab16043e66 100644
--- a/profiles/package.mask
+++ b/profiles/package.mask
@@ -134,11 +134,6 @@ dev-python/pykeepass
 dev-python/pg8000
 dev-python/scramp
 
-# Anna (cybertailor) Vyalkova <cyber+gentoo@sysrq.in> (2025-03-05)
-# Unmaintained in GURU, no revdeps.
-# Removal on 2025-04-05.
-dev-python/opentype-sanitizer
-
 # Julien Roy <julien@jroy.ca> (2024-03-21)
 # sys-libs/libucontext is masked in ::gentoo
 sys-libs/gcompat