diff --git a/dev-python/jupyter-sphinx/Manifest b/dev-python/jupyter-sphinx/Manifest
deleted file mode 100644
index 749e41d081..0000000000
--- a/dev-python/jupyter-sphinx/Manifest
+++ /dev/null
@@ -1 +0,0 @@
-DIST jupyter-sphinx-0.4.0.tar.gz 27538 BLAKE2B f293cbd7d01c47f6b9a9d288584934480c4349488feb6ddc65ea12b0acadead210a29dc170897c4bf9c7cfb4a01e6ec5bb4170c5fd6bc9dd52b6b5bd8af64751 SHA512 baca3d16f8680ddf1229d2d5bd1308e6055d4f26f955dd509ef9fea173728cfa4c09405d22181fd696176db5bc3a1ee33d3b4f5f6ff7691fb3a27b5b55af06a6
diff --git a/dev-python/jupyter-sphinx/jupyter-sphinx-0.4.0.ebuild b/dev-python/jupyter-sphinx/jupyter-sphinx-0.4.0.ebuild
deleted file mode 100644
index 1f144ffd71..0000000000
--- a/dev-python/jupyter-sphinx/jupyter-sphinx-0.4.0.ebuild
+++ /dev/null
@@ -1,29 +0,0 @@
-# Copyright 1999-2024 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=8
-
-DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{11..12} )
-
-inherit distutils-r1
-
-DESCRIPTION="Jupyter Sphinx Extensions"
-HOMEPAGE="https://github.com/jupyter/jupyter-sphinx"
-SRC_URI="https://github.com/jupyter/jupyter-sphinx/archive/v${PV}.tar.gz -> ${P}.tar.gz"
-
-LICENSE="BSD"
-SLOT="0"
-KEYWORDS="~amd64"
-
-RDEPEND="
- >=dev-python/sphinx-2[${PYTHON_USEDEP}]
- >=dev-python/ipywidgets-7.0.0[${PYTHON_USEDEP}]
- dev-python/ipython[${PYTHON_USEDEP}]
- >=dev-python/nbconvert-5.5[${PYTHON_USEDEP}]
- dev-python/nbformat[${PYTHON_USEDEP}]
-"
-DEPEND="${RDEPEND}"
-
-distutils_enable_tests pytest
-distutils_enable_sphinx doc/source dev-python/matplotlib dev-python/alabaster
diff --git a/dev-python/jupyter-sphinx/metadata.xml b/dev-python/jupyter-sphinx/metadata.xml
deleted file mode 100644
index 7360050560..0000000000
--- a/dev-python/jupyter-sphinx/metadata.xml
+++ /dev/null
@@ -1,10 +0,0 @@
-
-
-
-
-
- jupyter/jupyter-sphinx
- https://github.com/jupyter/jupyter-sphinx/issues/
- https://jupyter-sphinx.readthedocs.io
-
-
diff --git a/profiles/package.mask b/profiles/package.mask
index 5df9fac43b..35b3b0a4dd 100644
--- a/profiles/package.mask
+++ b/profiles/package.mask
@@ -144,11 +144,6 @@ dev-python/opentype-sanitizer
# Removal on 2025-04-05.
dev-python/notion-client
-# Anna (cybertailor) Vyalkova (2025-03-05)
-# Unmaintained in GURU, no revdeps left. Open bugs: #921892.
-# Removal on 2025-04-05.
-dev-python/jupyter-sphinx
-
# Julien Roy (2024-03-21)
# sys-libs/libucontext is masked in ::gentoo
sys-libs/gcompat